Source of Migraine identified

Scientists have identified an area of the brain that causes debilitating migraine headaches.

Researchers in France observing the brain scans of volunteers found that activity in the hypothalamus gland was associated with an attack. The gland, in the centre of the brain just above the brain stem, has long been suspected to play a role, as it regulates physiological responses to factors known to trigger attacks, such as hunger. Other researchers suggest that more than one region of the brain causes attacks.

The researchers, from Rangueil Hospital, Toulouse, used positron emission tomography, which contrasts activity within the brain, on seven patients with migraine without “aura” – the type that accounts for most migraines.

Such attacks last up to 72 hours and are characterised by pulsating headache, nausea and vomiting and sensitivity to light.

It is hoped that the discovery, featured in the journal Headache, could lead to future treatments for sufferers.